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In other examples, non-native glycosylation sites are introduced into the region of the heavy chain protease domain

O'Leary & Chahine, 2002)

For example, astrocyte-specific expression of SOCS3 in AD mouse models was shown to suppress not only GFAP induction and morphological hypertrophy but also neuroprotective and neurotoxic associated markers while simultaneously improving amyloid burden, synaptic function and cognition

UekiSMiyabeYYamamotoYFukuchiMHirokawaMSpencerLAet alCharcot-leyden crystals in eosinophilic inflammation: active cytolysis leads to crystal formation

933 BT2, a highly specific BCKD kinase inhibitor, promotes BCAAs oxidation by inhibiting BCKDHA phosphorylation, thereby reducing neuronal ferroptosis