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Even if a person is not deficient in Vitamin B12, as defined by a blood test, the symptoms of a B12 deficiency may include: Feeling weak or tired Problems with vision Headaches Pins and needles Reduced mental functions Wish to check you vitamin B12 levels

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One mechanism involves reducing transforming growth factor beta-1 secretion in fibroblasts

The potential of CD38-targeting sdAbs has been explored through the creation of different structures, such as chimeric antibodies, biparatopic antibodies, heavy chain-only antibodies, and half-life-extended nano-BiKEs, which show promise for the treatment of MM

10.1186/s13098-019-0484-0 107 PicardF.KurtevM.ChungN.Topark-NgarmA.SenawongT.Machado De OliveiraR.et al (2004)