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However, these transient bursts of immune activation are quickly neutralized by the dominant suppressive networks within the TME [57]

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However, this co-staining assay revealed no significant differences in RSL3-induced cell death rates between the control, WT, R62D, and S14C groups (Figures 2F,G), suggesting that nuclear F-actin assembly could be a concurrent feature rather than a determinant of ferroptotic sensitivity