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Treatment: If your doctor diagnoses your rash as a candida infection, treatment will likely involve a prescription antifungal medication

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Gastrointestinal issues: Conditions such as Crohn's disease, celiac disease, and irritable bowel syndrome (IBS) can damage the digestive tract making it harder for the body to absorb nutrients, including B12

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MTHFR variants like C677T can raise homocysteine and increase demand on the folate and B12 methylation pathway, but they do not by themselves cause deficiency