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According to clinical research parenteral administration (intramuscular or intravenous) is preferred over other drug administration routes in case of emergency situations as it provides first-pass metabolism avoidance, reliable therapeutic concentrations and better bioavailability of dosage (2) It can also be used in situations when oral route is not feasible

the number of published human cases is small

Note that the peak concentration occurs at the end of the constant rate input

This permanently damages the compounds structure, destroying its biological activity

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