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Donepezil (Cat No

H.CoulibalyB.StichA.ScheiweinM.MerkleH.EubelJ.et al

The excess ROS production in aging can initiate the pro-inflammatory generation through activation of multiple transcription factors, including human polynucleotide phosphorylase (hPNPaseold-35), nuclear factor kappa B (NF-B), activator protein 1 (AP-1), specificity protein 1 (Sp1), peroxisome proliferator-activated receptors (PPARs) [49, 50]

At present, drug and psychological treatments are the main treatments, but they produce insufficient responses in many patients and fail to work at all in many others