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Vitamin C restores ovarian follicular reservation in a mouse model of aging

362 In SLE, neutrophil-derived NETs can also suppress Treg differentiation by activating the TLR4 signaling pathway in nave CD4 T cells through S100A10

3.1.4.3 Strategies to bridge translational difficulties To improve clinical translatability, the following strategies are recommended: (1) Multi-species validation: mechanisms discovered in mice should be validated in rats, rabbits, or non-human primates