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X.McqueenT.HsuT.et al (2005)

Other agonists, such as the intestine-specific Fexaramine D (FexD), suppressed colitis-associated cancer (CAC) by restoring FXR signaling, enhancing intestinal barrier integrity, and reducing pro-inflammatory M1-like macrophage infiltration within the TIME ( Conversely, FXR inhibition or functional antagonism demonstrates therapeutic value where FXR activation is detrimental

Richard Austin, McMaster University, Canada Updates Copyright 2022 Li, Jin, Luo, Xu, Wu, Zhou, Wang, Xu, Jiao, Wang and Yang

This impressive array of cellular and molecular functions has raised considerable interest for the use of this substance as a nutritive supplement and also as a therapeutic agent

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