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Supporting this observation, publicly available transcriptomic data 28 from MOLT-4 (T-ALL) and REH (BCP ALL) cells cultured in either standard RPMI with 10% FBS or human CSF revealed a significant upregulation of CHAC1 , indicating that CSF itself activates stress response pathways associated with GSH depletion and induces lipid peroxidation ( Figure 3B , Sup

Biochimie 91 , 12731277 (2009)

ParkinsonA.2001 88

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Neurosci Lett 826:137715 Rigo JM, Hans G, Nguyen L, Rocher V, Belachew S, Malgrange B, Leprince P, Moonen G, Selak I, Matagne A (2002) The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA-and glycine-gated currents