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Abdominal pain is listed as the most common side effect, and few cases of gastrointestinal bleeding are also described (Fennell et al., 2007)

A putative role for platelet-derived growth factor in angiogenesis and neuroprotection after ischemic stroke in humans

Serine is critical for cancer progression, fueling macromolecule synthesis (proteins, lipids, nucleotides), antioxidant defense (glutathione production), and one-carbon metabolism (methylation, tRNA formylation) [13]

Buhr, E

In addition to the reason just stated, glutathione also contributes to drug resistance, which is why the pathway involved in glutathione production has become a major target for drug development