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Future success hinges on identifying CRC-enriched antigens, particularly on TME components (CAFs, CSCs) and leveraging payloads with robust bystander effects to overcome spatial heterogeneity (103)

In this study, starting from an in silico approach, we investigated novel potential therapeutic strategies to enhance the anti-tumor effect of trabectedin using in vitro and in vivo models of STS

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Their leukocytes, including monocytes and monocyte-derived macrophages (MDMs) do not produce TNF, even after stimulation with IFN

Inorganic nanoparticles can be produced through top-down or bottom-up methodologies

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