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[4] Graf MV, Kastin AJ, Coy DH, Fischman AJ

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The peptide suppresses pro-inflammatory cytokines including TNF-, IL-6, and TGF-, which are key drivers of chronic low-grade inflammation (inflammaging) in older skin

Moreover, GHK-Cu significantly inhibited the LPS-induced phosphorylation of p38 MAPK and slightly decreased the phosphorylation of JNK1/2, while having no observable effect on ERK1/2