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Western blot The cell protein was extracted using a radioimmunoprecipitation technique

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In addition to their roles in modulating the immune system, other functions have been attributed to exosomal cargo including enhanced vascular leakiness, fibronectin deposition, and delivery of soluble factors that are involved in ECM remodeling to support formation of a metastatic niche for tumor cells, including melanomas ( Figure 2 ) (104, 109112)

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