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Additionally, senescent cells produce matrix metalloproteinases (MMPs) and other proteolytic enzymes that disrupt the extracellular matrix, interfering with normal tissue structure and function

Vitamin D is important for everything from immune cell activation and modulation to inflammatory regulation, with direct influences on the lung epithelial cells and immune regulation in the lungs

Several epidemiological studies have also evidenced that hypercholesterolemia and increased oxysterol production are associated with higher cancer risk (e.g., postmenopausal breast cancer, colon cancer, lung cancer, non-Hodking lymphoma, acute mieloide leukemia) (95)

Chelators like transferrin and ferritin in the body regulate iron levels (Glin 2020)

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