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This enrolled 390 people with type 2 diabetes, all on insulin, and randomised them to metformin 850 mg three times daily or placebo, with a follow-up of just over 4 years (de Jager et al, 2010)

Think about it: most people wouldnt attempt to become a professional athlete without a coach

Recommendation: No b12 supplementation needed at start

Always include neuromuscular / proprioception work thats what protects your knee long term

Common signs include: Nasal congestion, itchy skin, or watery eyes Digestive upset such as bloating, abdominal pain, diarrhea, or nausea Systemic symptoms like fatigue, migraines, brain fog, or rapid heart rate This wide range of effects makes it easy to misdiagnose, especially since the symptoms fluctuate depending on food choices, stress, or environment