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This May be the Result of: old age as you age, your immunity declines physical and emotional stress the chemicals released by your body when youre stressed can lower your immune function HIV and AIDS people with HIV are much more likely to get Shingles, because of their weakened immune system Bone Marrow Transplant the conditioning you require before the transplant weakens your immune system Organ Transplant you may need to take medication to suppress your immune system so your body accepts the donated organ Chemotherapy chemotherapy medication, used to treat Cancer, temporarily weakens the immune system Young people who are otherwise healthy can also sometimes develop Shingles

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PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans