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Interleukin-4 receptor (IL4R), particularly type-II IL4R, is composed of IL4R and IL13R1, and it is upregulated in major tumors such as breast, lung, head and neck tumors and glioblastoma compared to their corresponding control tissues 23,24,25

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Collectively, our study establishes SYNCRIP as a central regulator that integrates transcriptional regulation, mRNA stability, and cap-independent translation to coordinate redox homeostasis and metabolic adaptation in GBM

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Copper acts as a critical cofactor that allows the peptide complex to participate in biological signaling and enzymatic processes