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Minimal adverse effects observed in preclinical models

Notwithstanding there are some similarities in the MGB axis disruption in these three groups in comparison to healthy subjects, it seems that these aberrations are greater in type I BD patients and melancholia [56]

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Nat Chem Biol (2017) 13(1):918

The cells were incubated at room temperature for 30 minutes in the dark, and the cell cycle was analyzed by flow cytometry (Win Bryte HS cytometer [Bio-Rad], using software Win Bryte, Bio-Rad Laboratories Inc., Hercules, CA, USA)