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Annual Meeting of the International Society for Pediatric Neurosurgery, Melbourne, Australia, 1998

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[41] showed that edaravone dexborneol effectively suppressed nucleotide-binding oligomerization domain-like receptor pyrin domain-containing protein 3 (NLRP3) inflammation-induced activation of microglial pyroptosis in experimental ischemic stroke through NF-B/NLRP3/gasdermin D (GSDMD) signaling pathway using transient MCAO (tMCAO) mouse model in vivo and oxygen-glucose deprivation (OGD) BV2 cell model in vitro

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Those given the lower dose had improved depression scores (Ashktorab 2022