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All stains were performed according to manufacturing protocols

Moreover, polyQ-expanded ataxin-3 was found to exacerbate TP53-dependent neurotoxicity, while maintaining strong binding and deubiquitination activity 103

Interestingly, accumulating evidence has identified that AIMPs participate in various physiological and pathological processes as multifaceted molecules 10,11,12,13

Pharmacological inhibition of mitochondrial carbonic anhydrases protects mouse cerebral pericytes from high glucose-induced oxidative stress and apoptosis