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Zang et al

Concurrently, oxidative stress-related enzymes exhibited distinct expression patterns

Currently, there are no standardized regulatory guidelines for the quality and validity of multiplex assays (193)

Plasma concentrations of insulin and leptin were measured using a custom developed Mesoscale (MSD) multiplex assay, which is a multi-array assay with electrochemiluminescence readout

The metabolically stabilized 6-AH family member, D-Nle-Tyr-Ile-NH-(CH 2 ) 5 -CONH 2 , had a t| /2 in blood of 80 min compared to the parent compound Norleual (Nle-Tyr-Leu-T-(CH 2 -N) 3 -His-Pro-Phe, SEQ ID NO: 1), which had a tj 2 in blood of Cm ax concentration in plasma extrapolated to time zero (Co), terminal elimination half-life (ti 2 ), volume of distribution (Vd), and clearance (CL)