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Expression of TfR1 was increased, while expression of an iron storage protein complex which includes ferritin heavy chain 1 (FTH1) and ferritin light chain (FTL) was decreased during ferroptosis, indicating the increase in iron uptake and decrease in iron storage during this process (Gao et al., 2015)

To improve the efficiency of the cascade, we evaluated the catalytic rates of the individual enzymes

Equally critical is serines contribution to redox balance through glutathione (GSH) and NADPH generation, which scavenge reactive oxygen species (ROS) and mitigate oxidative stress, a key mechanism of chemotherapy resistance [13, 51, 52]

Food Bioscience, 42 , 101168

however, this is not the only source that can cause oxidative stress in body