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The 50, 12.5 and 10 M data (test concentrations) were withheld to be used for blind validation

AKT activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart

J.MaityS.MadeshM.et al (2020)

Their highly electrophilic N=C=S core reacts readily with many biological nucleophiles 14 , through conjugation to exposed nucleophilic residues and cleavage of disulfide bonds, resulting in the disruption of protein tertiary structures and active sites 15,16

119-47-1 Appearance Solid Molecular Weight 340.50 Formula C 23 H 32 O 2 Color White to off-white SMILES OC1=C(C(C)(C)C)C=C(C)C=C1CC2=CC(C)=CC(C(C)(C)C)=C2O Structure Classification Initial Source spergillus fumigatus Shipping Room temperature in continental US