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Lifehacks: If you think you may need to boost your glutathione levels due to oxidative stress and genetic polymorphisms, there are multiple way you could approach this: Reduce the need for glutathione (reduce toxins) Add more cysteine-rich foods its the limiting factor for glutathione synthesis Also, add glycine if it is limited in your diet Directly supplement with liposomal or IV glutathione Indirectly supplement with cofactors, amino acids (caution here) Avoiding toxicants: Avoiding exposure to the toxicants that deplete glutathione will increase your overall glutathione levels and give you more resistance to oxidative stress

PLoS Pathog 2 , e59 (2006)

At the molecular level, glutathione protects the delicate protein complexes of the mitochondrial electron transport chain (ETC)

This complexation is what makes the molecule biologically active and effective

Deficient eNOS phosphorylation is a mechanism for diabetic vascular dysfunction contributing to increased stroke size