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CagriSema leverages two individually validated components and is further along in development (phase 3 completed)

It can, in a limited way

No NAFLD patient had clinical evidence of hepatic decompensation, such as hepatic encephalopathy, ascites, variceal bleeding, or a serum bilirubin level greater than twice the upper limit of normal

Conversely, men may be underdiagnosed until more advanced neurological or cardiovascular manifestations occur, suggesting that under-screening contributes to delayed recognition

Biochem Biophys Res Commun Dual-cardiotoxicity evaluation of torsadogenic risk drugs using human iPSC-derived cardiomyocytes