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Although rats have some physiologic differences from humans in the absorption, transport, and metabolism of vitamin B-12, these findings raise the alternative hypothesis that the effect of metformin on circulating vitamin B-12 concentrations is not due to the inhibition of absorption but rather due to the redistribution of vitamin B-12 among tissue compartments

GLP-1 agonists produce larger absolute weight reductions (1520% over 68 weeks in clinical trials), but the MOTS-c stack may preserve lean mass more effectively due to AMPKs role in muscle glucose uptake and mitochondrial biogenesis

Intermediate role of gut microbiota in vitamin B nutrition and its influences on human health

Romanian Journal of Diabetes Nutrition and Metabolic Diseases 28(4):352362 Negi A, Pasam T, Dandekar MP (2022) Acute and subacute administration of bacillus subtilis UBBS-14 probiotic shows no toxicity in male and female sprague-dawley rats