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"Centenarians display plasma MOTS-c concentrations significantly higher than age-matched peers, a pattern that closely resembles levels found in individuals decades younger suggesting preserved mitochondrial signaling as a hallmark of exceptional longevity." The connection to cellular senescence deserves further attention here

The studies summarized in Table 1 provide evidence of persistent microbiome alterations in long COVID

This is especially important for people on highly restrictive eating plans, older adults, vegetarians, vegans, or those with certain digestive or absorption issues

Skin may appear slightly more hydrated