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doi: 10.3389/or.2026.1814601 Received 20 February 2026 Revised 17 April 2026 Accepted 20 April 2026 Published 11 May 2026 Volume 20 - 2026 Edited by Vivek Verma, University of Minnesota Twin Cities, United States Reviewed by Wojciech Micha Jankowski, Medical University of Lodz, Poland Hao Guo, Xiamen University, China Updates Copyright 2026 Nemani and Rieger

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People with abnormal liver function or a history of liver disease, diabetes, active peptic ulcer disease, gout, cardiac arrhythmias, inflammatory bowel disease, migraine headaches, or alcoholism may be more susceptible to the adverse effects of excess niacin intake than the general population (41)

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