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Reactive oxygen species, granulocytes, and NETosis

CXCL8 plays an important role in inflammatory diseases and tumors (151)

Front Pharmacol 11:624529 Wang Y et al (2021) Involvement of REV-ERB dysregulation and ferroptosis in aristolochic acid I-induced renal injury

For example, a previous study demonstrated that the ferroptosis inhibitory activity of ferrostatin-1 and liproxstatin-1 is likely driven by their reactivity as radical-trapping antioxidants rather than their potency as inhibitors of lipoxygenases (81)