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Amino Acids 45:133142 Aoyama K, Suh SW, Hamby AM, Liu J, Chan WY, Chen Y, Swanson RA (2006) Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse

Taken together, these data show that NRF2 and ChaC1 negatively affect the expression of the other

The reduction of roGFP2(S 2 ) is therefore a good example for an enzyme using an alternative reaction pathway to overcome a kinetic challenge, and we hypothesize that other non-glutathione disulfide substrates with reactive proximal cysteinyl residues and rather negative redox potentials also require a ternary complex for their reduction

It should be noted that BMI was not considered for the UFM vs ND comparisons

The polyphenols in green tea work together with glutathione to provide stronger antioxidant protection