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It activates MC1R as well as MC3, MC4, and MC5 receptors, which affect bodily functions, including appetite, sexual arousal, and blood pressure regulation

[DOI] [PubMed] [Google Scholar] 43.McLean N., Tighiouart M., Muller S

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They may indicate a patient's predisposition to melanoma, particularly if there is a family history of melanoma (atypical mole or dysplastic naevus syndrome)