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EPP is the primary approved clinical indication for Afamelanotide and has generated the most extensive translational research programme characterising MT-1s photoprotection mechanisms in human subjects

For white individuals in the United States, the chance of getting melanoma in their lifetime is generally less than 1%

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y de pigmentaciones difusas o multifocales como melanoma, sarcoma de Kaposi, pigmentacin racial, sndrome de Peutz-Jeghers, Neurofibromatosis, enfermedad de Addison, pigmentacin asociada a VIH, y lengua negra pilosa