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Neurology 38 , 12851291 (1988)

For children with MTHFR mutations, supplementing with methylated forms of vitamins B12 and folate as well as other methylated compounds might be necessary

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Hydration Support elimination/excretion via the kidney Sweating (movement, saunas, etc.) Support elimination/excretion via dermal routes Optimize Nutrition Focus on a whole foods diet to maximize fiber and nutrient density Judicious Use of Supplements and/or Pharmaceuticals Personalization of the therapeutic journey is key as each patients presentation and history is unique