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Looking beyond GLP-1 and insulin as payloads (a molecule that increasingly appears to be a poor commercial candidate), 29 at least ten companies are working on device-based solutions to administer proteins and monoclonal antibodies orally and some technologies including the RaniPill have reached Phase I

Dennis CV, Suh LS, Rodriguez ML, Kril JJ, Sutherland GT

Beyond their structural role, they contribute to energy production by entering the TCA cycle through deamination [8]

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