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Gut microbiota and Parkinson's disease: exploring pathogenesis and potential therapeutic strategies from a gut brain axis perspective ScienceDirect Depletion of dopamine in Parkinson's disease and relevant therapeutic options: A review of the literature PMC Revamping Parkinson's disease therapy using PLGA based drug delivery systems PMC The glutathione system in Parkinson's disease and its progression ScienceDirect Dietary Antioxidants and Parkinson's Disease PMC

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Good sleep hygiene consistent bedtime, minimal bluelight exposure, stress reduction, and avoiding stimulants before bed will enhance the effects of DSIP (or any sleep promoting substance) far more than simply boosting dose

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In addition, chronic alcohol consumption shifts the substrate of oxidation from carbohydrates to lipids and increases acetyl-CoA availability because of increased adipose tissue lipolysis [205]

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