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FEBS Lett 563:185190 Gao Y, Hannan NR, Wanyonyi S, Konstantopolous N, Pagnon J, Feng HC, Jowett JB, Kim KH, Walder K, Collier GR (2006) Activation of the selenoprotein SEPS1 gene expression by pro-inflammatory cytokines in HepG2 cells

Heavy Metals Mediate CVD through Oxidative Stress Mechanisms Atherosclerosis begins when lipids are able to pass through the damaged endothelium into the blood vessel wall, a process initiated and mediated by oxidative stress (26)

15 , a041222 (2023)

Thymoquinone ameliorates lead-induced brain damage in Sprague Dawley rats

Activated ATF3 then recruits HDAC1 to pro-inflammatory gene promoters (143,163), thereby reducing H3/H4 histone acetylation (138,164) and counteracting Rel/NF-B transcriptional activity (115,164,165)