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HYGIENE A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS A61P15/00Drugs for genital or sexual disorders

Glutamine-derived -KG can enter the TCA cycle to produce energy for the cell or proceed backwards via the reductive carboxylation to provide an alternative source of lipid synthesis

Enhanced expression of CD47 is associated with off-target resistance to tyrosine kinase inhibitor gefitinib in NSCLC

When recruited, it becomes oligomerized and is transported to mitochondria where it interacts with protein adaptors, such as the mitochondrial fission factor (Mff), the mitochondrial fission protein 1 (Fis1), the mitochondrial dynamics protein 49 (MiD49/MIEF2), and the mitochondrial dynamics protein 51 (MiD51/MIEF1) [315]