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In a clinical setting, a low white cell count is called leukopenia

Side effects from B12 supplementation are uncommon but may include: Mild gastrointestinal symptoms such as nausea or diarrhoea, typically with very high oral doses Headache or dizziness in some individuals Skin reactions (rash, itching) at injection sites when using intramuscular preparations Rare but serious allergic reactions, including anaphylaxis with injectable forms Hypokalaemia (low potassium) may occur during rapid correction of severe megaloblastic anaemia If you experience symptoms of a severe allergic reaction (difficulty breathing, severe rash, swelling of face or throat) after taking B12, seek immediate medical attention

This can interfere with your performance at school, potentially leading to poor grades and attendance, or at work, harming your ability to keep your job

iScience 27 , 110095 (2024)

the FDA advisory committee then voted against permitting their compounding, leaving them restricted (source)