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In contrast, good fits with concentration-independent rate constants were obtained for the monothiol mechanism (iii) from Fig

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Although clinical trials have so far failed to demonstrate relevant clinical benefits of antioxidant (such as vitamin C, vitamin E, and -lipoic acid) to treat T2DM 34 , here we show that TdGSH can fully prevent LOsG/ROS-induced detrimental effects on -cells

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Current therapeutic approaches are directed at controlling symptoms and delaying the progression of the disease for as long as possible (Poewe, 2009)