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When this balance is disrupted, oxidative stress occurs

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The quality control sample was made with 25 L National Institute of Standards and Technology (NIST) standard plasma sample dissolved in 100 L of extraction buffer (methanol/water 50/50) containing 250 ng/mL of debrisoquine (DBQ) as internal standard for positive mode and 250 ng/mL of 4-nitrobenzoic acid as internal standard for negative mode