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Comparison of serum microbiome composition in bipolar and major depressive disorders

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Furthermore, the copper transporter ATP7A has been identified as a novel ferroptosis regulator, as its deficiency downregulates the cystine transporter SLC7A11, impairing GSH synthesis and sensitizing cells to ferroptosis [72]

MATERIALS AND METHODS Materials: Methamphetamine hydrochloride, CoQ10, 5,5-dithiobis (2-nitrobenzoic acid), 1-methyl-2-phenylindole butylated hydroxytoluene, glutathione reductase enzyme, Nicotinamide adenine dinucleotide phosphate (NADPH), hydrogen peroxide, pyrogallol, Triton X-100, EDTA, all buffers and other reagents were purchased from Sigma-Aldrich

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