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In general, plants own very competent enzymatic [catalase (CAT), monodehydroascorbate reductase (MDHAR), superoxide dismutase (SOD), ascorbate peroxidase (APX), glutathione reductase (GR), dehydroascorbate reductase (DHAR), guaiacol peroxidase (GPX)] and non-enzymatic [glutathione (GSH), ascorbic acid (AsA), carotenoids, alkaloids, phenolic compounds as well as non-proteinaceous amino acids] antioxidative defensive systems which act in collaboration to regulate the problems of unrestrained oxidation and ultimately shield the plant cells from oxidants injury by scavenging these toxic ROS [11]

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Comparative and functional genomic resource for mechanistic studies of human blood pressure-associated single nucleotide polymorphisms

recently reported that IDO1 is upregulated in response to amyloid and tau pathology in astrocytes, leading to increased production of kynurenine (KYN)