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Description

Its structure is a faithful, full-sequence mimic of -MSH

Adrenergic and cholinergic control in the biology of epidermis: physiological and clinical significance.The Journal of Investigative Dermatology

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Receptor activation triggers adenylyl cyclase signaling, elevating intracellular cAMP, which activates protein kinase A (PKA) and subsequently the MITF (melanocyte-inducing transcription factor) pathway

Although PIN usually presents as red macules, papules, nodules or plaques, it may present as diffuse redness of the glans and inner foreskin (balanoposthitis)