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F.ChiN.BechardM.LavioletteS

Engineered urinary-derived extracellular vesicles loaded nanoenzymes as trojan horses to regulate the inflammatory microenvironment for treatment of alzheimers disease

In this study, we examine the change in phosphorylated MDM2(Ser166) (p-MDM2(Ser166)) in neuronal cells treated with glutamate alone or in combination with 4-OH-E 1

Cytosolic and mitochondrial pools of malate and OAA are connected by two transporters the malate-2OG transporter (Slc25a11) and the glutamate-aspartate transporter (Slc1a3) and by the interconversion of aspartate and glutamate into OAA and 2OG by the cytosolic and mitochondrial isoforms of the glutamate-oxaloacetate transaminase, Got1 and Got2, respectively