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This essential vitamin helps your brain:53 54 Create neurotransmitters, amino acids, and proteins Regulate energy use in the brain Maintain proper brain and immune system development and functioning B6 deficiencies have been linked to cognitive impairment,40 seizures,41 migraine,42 anxiety,43 and depression (particularly in those taking oral contraceptives).44 45 Some experts theorize that vitamin B6 is so good for the brain because its one of the vitamins that helps the body break down homocysteine, an amino acid byproduct associated with dementia, heart disease, and stroke in high concentrations.55 You dont make vitamin B6 naturally, so healthy adults need to get about 1.3mg of it daily.46 It isnt clear if getting more than the recommended amount improves cognition beyond mitigating the effects of a deficiency