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minuta ) inhibits the PI3K-Akt pathway by upregulating IGF-1 expression, promotes macrophage polarization toward M2, and reduces pro-inflammatory factor production ( Abnormal regulation of apoptosis, a key metabolic process for maintaining intestinal homeostasis, is closely associated with intestinal mucosal barrier damage in UC

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The amplified products were recombined and transformed on ice using DH5 competent cells, based on which the sequence for the plasmid was extracted and confirmed

Notably, the enzyme responsible for the reduction of vitamin K, crucial for ferroptosis inhibition, was identified as FSP1, previously known as extramitochondrial CoQ 10 reductase [11, 13]