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Radiat Phys Chem, pp 112941 Ravimoorthy R, Pottail L, Kotakonda M (2025) Solar-assisted synthesis of silver nanoparticles from Amphilophium paniculatum (L.) Kunth: unlocking multi-therapeutic potential for lung cancer, diabetes and drug resistant infections through in vitro studies and in silico antidiabetic evaluations

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In addition, as autophagy may play a protective role against ER stress and rejuvenate organelle function, impaired autophagy may lead to mitochondrial dysfunction and ER stress, which have been implicated as causes of insulin resistance

We observed that it could be utilized as a sulfur source, but in this case, its transport was dependant on the glutathione transporter OPT1/HGT1 and not on SEO1 (Fig 4b)

Based on the skeleton of 2-amino-3-cyano-6-(2-hydroxy-phenyl)pyridine, a series of inhibitors were designed and synthesized, yielding compounds 69-74 [180, 181]