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During this process, acetyl-CoA produced by the pyruvate dehydrogenase (PDC) complex in muscle exceeds the processing capacity of the tricarboxylic acid (TCA) cycle

Moreover, the intense sensation of hunger in the CT group may force participants to ingest more than allowed by the study design

Attarian 2011): Neoadjuvant chemotherapy , sometimes called induction chemotherapy , is given prior to surgery or radiotherapy in order to shrink the original (primary) tumor