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As NAD+ supplementation research has expanded dramatically, the discovery that NNMT depletes NAD+ precursors specifically in metabolically dysfunctional fat tissue provides a targeted intervention point

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Here are some times to consider changing the dose: If treatment isnt working well, increase the dose or how often its given If B12 levels are too high, lower the dose Change the dose if the patients health changes or new issues come up By sticking to these guidelines, doctors can make B12 treatment better for each patient