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Combined GHRH + GHRP/ghrelinmimetic administration produces synergistic, amplified GH pulses compared to either agent alone [1] [2]

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For short-acting peptides such as Sermorelin (t ~1120 min), Tesamorelin (t ~26 min), and AOD-9604 (t ~30 min), pulsatile administration once or twice daily is the predominant research approach